Across the sample, the increase in frequency of use was significantly associated with poorer pain intensity and interference and a worse negative effect, although high-frequency users also reported an improvement in the positive effect. CBD is emerging as a promising pharmaceutical agent for treating pain, inflammation, seizures and anxiety without the psychoactive effects of THC. Our understanding of the role of CBD in treating pain continues to evolve, and evidence from animal studies has demonstrated that CBD exerts its analgesic effects through its various interactions and the modulation of the endocannabinoid, inflammatory and nociceptive (pain detection) systems. The endocannabinoid system consists of cannabinoid receptors that interact with our own natural cannabinoids.
This system is involved in the regulation of many body functions, such as metabolism and appetite, mood and anxiety, and the perception of pain. Many people use cannabidiol (CBD) to relieve pain. Understanding CBD can help overcome the stigma associated with it. However, scientists believe that CBD may help alleviate anxiety.
That, in turn, could affect a person's perception of pain and potentially make them feel more comfortable. However, the research is still under way and it is too early to draw anything conclusive. The worsening pain caused by cannabis is a real phenomenon. It was reported by several people and has been replicated in a laboratory environment.
They also provided guidance to the Arthritis Foundation, which recently surveyed 2,600 people with arthritis and found that 29% currently use CBD to treat arthritis symptoms. Given its promising results in animal models, along with its relative safety, its non-psychoactive properties and its low potential for abuse, CBD is an attractive candidate for pain relief. And in states where CBD is legal, laws may vary as to the amount of THC allowed in CBD products to be legally sold. People report using CBD for anxiety, pain and sleep, everything that goes hand in hand with chronic pain, he says.
Although there may be a dose level that relieves pain, even a slightly higher dose can reverse the effect and worsen pain. While CBD is a promising option for pain relief, research has not yet proven to be safe and effective, and the Food and Drug Administration (FDA) has not approved CBD for treating pain. Researchers understand CBD much less than THC, although there is anecdotal evidence that it may ease pain in some people. Until there is high-quality scientific evidence in humans, it is difficult to make a recommendation for the regular use of CBD in the treatment of chronic pain.
There are currently no high-quality research studies that support the use of CBD only for the treatment of pain. Many people are turning to CBD as an alternative pain reliever, especially in light of the opioid crisis, which in a commentary published in the Annals of Internal Medicine, Boehnke and Daniel Clauw, M. CBD oil is especially promising because of its lack of intoxicating effects and its possible lower potential for effects side effects. more effects than many other pain relievers.
According to the National Centers for Complementary and Integrative Health (NCCIH), some evidence suggests that cannabis or CBD may have modest benefits for chronic pain. Given the rapid change in the legality of cannabis, coupled with the increase in appetite for something new and the push for unprecedented profit margins, the advertising of cannabinoids in general and CBD in particular has gone crazy.